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用低剂量IL-2,同时加入人RBC诱导制备同种异体LAK细胞,可见LAK细胞的增殖明显和杀伤活性显著提高。用自制的复方白细胞介素2及LAK细胞组成LAK细胞联合复方白细胞介素2(LAK/IL-2Co.)过继免疫疗法和联合放疗、化疗的综合疗法,共治疗中、晚期恶性肿瘤138例,疗效结果判定,单纯免疫疗法治疗组,无CR,PR30.3%,综合疗法治疗组CR+PR为58%,且副反应均较轻,本项应用研究结果是安全有效的,能作为抗肿瘤优选的治疗方案
With the use of low dose of IL-2 and simultaneous addition of human RBC to induce allogeneic LAK cells, the proliferation and killing activity of LAK cells were significantly increased. Using self-made compound interleukin 2 and LAK cells, LAK cells combined with compound interleukin 2 (LAK/IL-2Co.) adoptive immunotherapy and combined radiotherapy and chemotherapy combined therapy to treat 138 cases of middle and late stage malignant tumors. The efficacy results showed that only immunotherapy group, no CR, PR30.3%, comprehensive treatment group CR+PR was 58%, and the side effects were mild, the results of this application study is safe and effective, can be used as anti-tumor optimal Treatment programs