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目的：讨论有关急性闭塞性脑血管病，使用尿激酶选择性动脉内溶栓治疗问题。方法：选用股动脉置管，脑血管造影后，将导管选择性进入阻塞部位，注入尿激酶进行溶栓治疗，一般药量为50万U～100万U，时间为30分钟～45分钟。结果：神经功能完全恢复者19例，轻度功能障碍者10例，1例单瘫，1例死亡。结论：造择性动脉内溶栓是治疗急性闭塞性脑血管病安全有效，首选的治疗方法，选用时尤应注意治疗应在发病6小时以内，最多不超过16小时。
PURPOSE: To discuss the use of urokinase-selective intra-arterial thrombolysis in the management of acute occlusive cerebrovascular disease. Methods: Choosing femoral artery catheter and cerebral angiography, the catheter selectively into the obstruction site, urokinase injection thrombolytic therapy, the general dose of 500 000 U ~ 1000000 U, time is 30 minutes to 45 minutes. Results: Nineteen patients with complete recovery of nerve function, 10 patients with mild dysfunction, 1 patient with single paralysis and 1 patient died. Conclusion: The selective intra-arterial thrombolysis is a safe and effective treatment for acute obliterative cerebrovascular disease. The treatment should be treated with special attention. The treatment should be within 6 hours and up to 16 hours.