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再发性风湿病包括单关节炎或少数关节炎的自限性再发性发作,可发展为典型的类风湿性关节炎。作者报告对氯喹有明显疗效的3例患者。例1为33岁男性,间歇性疼痛,肩、肘、腕、掌指关节肿胀及双膝呈典型的再发性风湿病史已5年。多种抗炎剂均无效。因每周发作5次而产生严重病废,采用氯喹250mg/d 治疗。服首剂后即感好转,此后未复发并完全恢复活动,继续隔日用药。因视网膜电图异常而于2年后停用此药,其后3个月内有过2次轻度发作,此后7年未作任何治疗也无发作。例2为19岁女性,再发性的手指、双膝及双踝疼痛肿胀已8
Recurrent rheumatoid arthritis, including a single or a few self-limiting recurrent episodes of arthritis, can develop into a typical rheumatoid arthritis. The authors report 3 patients who had a significant effect on chloroquine. Case 1 was a 33-year-old man with intermittent pain, swollen shoulders, elbows, wrists, metacarpophalangeal joints and a typical history of recurrent rheumatism on both knees for 5 years. A variety of anti-inflammatory agents are ineffective. Seizures due to 5 times a week and serious illness caused by waste, the use of chloroquine 250mg / d treatment. After the first dose of the drug, the flu improved. After that, the patient did not relapse and fully recovered from the activity, and the medication was taken every other day. The drug was discontinued after 2 years due to an abnormal electroretinogram, with 2 mild attacks within the next 3 months and no further 7 years after surgery. Case 2 was a 19-year-old female with recurrent fingers, swelling of the knees and ankle pain 8