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对54例成人巨细胞病毒(CMV)感染分3组进行临床分析。(1)CMV单核细胞增多症;以发热明显而症状消遥,一过性肝功能损害,血液学改变类似传染性单核细胞增多症而EB病毒指标阴性为特征。并发症复杂但预后好。(2)CMV肝炎:临床表现与其他病毒性肝炎相似。以急性黄疸型恢复最快,单纯转氨酶升高次之,无黄疸型较慢。单纯CMV肝炎预后好。(3)免疫缺损者CMV感染;75%病例于免疫抑制治疗后发病。体温高,并发症凶险,半数病人死亡。建议对不明原因高热、肝炎、肺炎,特别是免疫缺损者,要考虑CMV感染的可能。
54 cases of adult cytomegalovirus (CMV) infection were divided into 3 groups for clinical analysis. (1) CMV mononucleosis; characterized by marked fever and symptoms, transient liver damage, hematological changes similar to infectious mononucleosis and EB virus negative. Complicated complications but good prognosis. (2) CMV hepatitis: clinical manifestations and other viral hepatitis similar. Acute jaundice recovery fastest, followed by elevated aminotransferases, jaundice-type slower. Simple CMV hepatitis good prognosis. (3) CMV infection in immunocompromised patients; 75% of cases developed after immunosuppressive therapy. High temperature, dangerous complications, half of the patients died. Proposed for unknown causes of fever, hepatitis, pneumonia, especially immunodeficiency who, to consider the possibility of CMV infection.