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以往发现癌细胞是通过比较细胞形态、细胞及其核的大小等进行判断的,但应用此法必须具备病理学者那样丰富的经验。福井医科大学的福田教授研究出利用荧光染色鉴别癌细胞的方法,这将大大有助于癌的早期发现。癌细胞的DNA 结构不稳定,容易裂解。因此,福田教授将正常细胞和从患者摘取的癌细胞混合的剥离细胞用稀盐酸加水分解。这样,DNA 的不稳定部分裂解,双链变为单链。若再加入吖啶橙溶液(AO),则仅癌细胞被染成
In the past, cancer cells were judged by comparing the morphology of cells, the size of cells and their nuclei, but the application of this method must have as much experience as a pathologist. Professor Fukuda from Fukui Medical University has developed a method for identifying cancer cells using fluorescent staining, which will greatly contribute to the early detection of cancer. The DNA structure of cancer cells is unstable and easily cleaves. Therefore, Prof. Fukuda hydrolyzed hydrolyzed exfoliated cells mixed with normal cells and cancer cells extracted from patients with dilute hydrochloric acid. In this way, the unstable portion of DNA is cleaved and the double strand becomes single-stranded. If only acridine orange solution (AO) is added, only cancer cells are stained