本文综述了近年来基于环糊精包合作用的超分子水凝胶的研究进展,主要包括:环糊精与线性、星型、接枝、超支化聚合物包合形成的多聚(准)轮烷自组装制备超分子物理凝胶及功能化多聚(准)轮烷经交联反应制备超分子化学凝胶;环糊精、环糊精二聚体及其水溶性聚合物与带疏水性侧基的聚合物经“锁-钥匙”包合作用形成超分子物理凝胶;及其在药物、基因释放载体与组织工程支架中的应用。着重介绍了剪切、温度、pH值、光等刺激-响应性超分子水凝胶的设计与制备。 In this paper, the progress of the research on supramolecular hydrogels based on inclusion of cyclodextrins in recent years are summarized, including: the formation of poly (quasi) Preparation of supramolecular chemical gels and functionalized poly (quasi) rotaxanes by self-assembly of rotaxanes Preparation of supramolecular chemical gels by cross-linking reaction; cyclodextrin, cyclodextrin dimers and their water-soluble polymers with hydrophobic The polymer of the pendant group forms a supramolecular physical gel through the inclusion of a “lock-key” and its application in drug delivery, gene delivery vectors and tissue engineering scaffolds. The design and preparation of stimulus-responsive supramolecular hydrogels with shear, temperature, pH and light are emphatically introduced.