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目的:研究食管癌在三维适形放疗中联合应用注射用艾迪注射液增敏和降低放疗副反应作用。方法:72例食管癌患者随机分成两组;一组行单纯三维适形放疗(单放组),2Gy/次,5次/W,总剂量64Gy,6.4周完成;另一组在三维适形放疗的同时加用艾迪注射液(综合组)50ml加入5%GS 500毫升缓慢静脉滴注,放疗期间同步使用,每日一次,每周五次。结果:治疗组与对照组长期疗效(随访一年CR+PR)分别为72.2%和47.2%,经统计学处理后两组比较P<0.05,有统计学差异;血液毒性方面,治疗组及对照组均出现Ⅰ~Ⅱ度的白细胞减少,发生率分别为10.0%、30.4%,两组比较P<0.05,有统计学差异。结论:食管癌三维适形放疗的同时加用艾迪注射液,具有增敏和降低放疗副反应作用。
Objective: To study esophageal cancer in three-dimensional conformal radiotherapy combined with injection of Aidi injection sensitization and reduce side effects of radiation. Methods: A total of 72 patients with esophageal cancer were randomly divided into two groups. One group received simple three-dimensional conformal radiotherapy (single radiotherapy group, 2Gy / time, 5 times / W, total dose 64Gy, Radiotherapy plus Aidi injection (integrated group) 50ml added 5% GS 500 ml slow intravenous infusion, simultaneously with radiotherapy, once daily, five times a week. Results: The long-term effect (CR + PR one year follow-up) of the treatment group and the control group was 72.2% and 47.2% respectively. There was statistical difference between the two groups after statistical treatment (P0.05). In the aspect of hematotoxicity, Group Ⅰ ~ Ⅱ degree of leukopenia occurred, the incidence rates were 10.0%, 30.4%, P <0.05, the two groups were statistically significant. Conclusions: Three-dimensional conformal radiotherapy of esophageal cancer plus Aidi injection, with sensitization and reduce the side effects of radiotherapy.