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目的:分析克罗恩病(Crohn病,CD)的临床表现多样性及误诊的主要原因。方法:对5 a收治的10例CD患者的临床表现、内镜及实验室查结果及诊治经过进行分析,分析本病的临床多样性特点及误诊原因。结果:10例患者中,病变侵犯胃肠道任一部位。症状:腹痛、腹泻为主要表现;尚有腹泻与便秘交替、便血。肠外表现多见于发热、贫血、消瘦、皮疹、肾结石、胆石症、口腔溃疡、关节痛。内镜有跳跃式分布的溃疡、息肉、狭窄、或卵石样改变与增殖性病变并存的特点。结论:本病临床表现缺乏特异性,症状多样化,X线检查、内镜联合活检是及时、正确诊断的关键。
Objective: To analyze the clinical manifestations of Crohn’s disease (CD) and the main causes of misdiagnosis. Methods: The clinical manifestations, endoscopic and laboratory findings and diagnosis and treatment of 10 cases of CD in 5 years were analyzed to analyze the clinical features of the disease and the causes of misdiagnosis. Results: In 10 patients, the lesion invading any part of the gastrointestinal tract. Symptoms: abdominal pain, diarrhea as the main performance; there are alternating diarrhea and constipation, blood in the stool. Extraintestinal manifestations more common in fever, anemia, weight loss, rash, kidney stones, cholelithiasis, oral ulcers, joint pain. Endoscopic skip distribution of ulcers, polyps, stenosis, or coexistence of pebble-like changes and proliferative lesions. Conclusion: The clinical manifestations of the disease is lack of specificity, symptoms, X-ray examination, endoscopic biopsy is the key to timely and correct diagnosis.