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目的:探讨米索前列醇用于人工流产前促进宫颈成熟的临床疗效。方法:248例人工流产手术患者随机分为观察组和对照组各124例,观察组术前给予米索列醇研磨成粉放置于阴道后穹窿部治疗,对照组不使用任何促使宫颈成熟的药物。观察两组患者的宫颈扩张情况、疼痛程度、手术时间和术中出血量。结果:观察组有效率为96.8%,明显高于对照组的82.3%(P<0.05);观察组疼痛程度较对照组改善明显(P<0.05),手术时间明显短于对照组,术中出血量也明显低于对照组(P<0.05)。结论:米索前列醇研磨成粉用于人工流产术前,可以有效松弛宫颈,缩短手术时间,减轻患者痛苦,降低手术难度,值得临床推广。
Objective: To investigate the clinical effect of misoprostol for promoting cervical ripening before induced abortion. Methods: 248 cases of induced abortion were randomly divided into observation group and control group, 124 cases in each group. The observation group was treated with misoprostol and ground into powder for vaginal fornix treatment. The control group did not use any drug to promote cervical ripening . Two groups of patients were observed cervical dilatation, pain, surgery time and intraoperative blood loss. Results: The effective rate in the observation group was 96.8%, which was significantly higher than that in the control group (82.3%, P <0.05). The degree of pain in the observation group was significantly improved compared with that in the control group (P <0.05), and the operation time was significantly shorter than that in the control group The amount was also significantly lower than the control group (P <0.05). Conclusion: Misoprostol is ground into powder for artificial abortion before surgery, which can effectively relax the cervix, shorten the operation time, alleviate the suffering of patients and reduce the difficulty of operation, which is worthy of clinical promotion.