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目的:不同剂量孕激素治疗无排卵型月经失调的临床疗效观察。方法:选取2015年5月到2016年7月来我院就诊的月经失调患者160例,分为A、B、C、D四组每组40例,分别给予四组患者100mg/d、200mg/d、300mg/d、400mg/d孕激素进行治疗。治疗后对比分析四组患者的临床疗效和四组患者子宫内膜厚度以及不良反应发生率。结果:治疗后,A、B、C、D四组患者子宫内膜厚度差异不显著(P>0.05),无统计学意义;A、B、C、D四组患者治疗后,临床疗效分别为95.0%,97.5%,95.0%,92.5%,差异不显著(P>0.05),无统计学意义;B、C、D三组患者不良反应发生率均远高于A组患者,差异显著(P0.05), no statistical signiifcance;A, B, C, D four groups of patients after treatment, the clinical curative effect were 95.0%, 97.5%, 95.0%, 92.5%, no signiifcant difference (P>0.05), no statistical signiifcance;B, C, D, incidence of adverse reactions in patients with three group were much higher than A group of patients, signiifcant difference (P<0.05), with statistical signiifcance. Conclusion:different type anovulatory menstrual disorder dose progestogen therapy clinical curative effect was not signiifcant, and with the increase of the dose patients will improve the incidence of adverse reactions, thus, should choose small dose of treatment in the clinical treatment in order to reduce the incidence of adverse reactions.