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目的:观察短时体外受精(IVF)和单精子卵胞浆内显微注射(ICSI)技术对严重少弱精患者的疗效。方法:回顾性分析接受50个周期辅助生殖治疗的精液参数为严重少弱精患者的治疗结果。结果:17周期IVF受精,IVF受精率低于ICSI,差异有统计学意义(P<0.05),但两组可用胚胎数和优胚数比较差异无统计学意义(P>0.05)。33周期IVF受精失败,31周期行Re-ICSI。同源卵子ICSI与Re-ICSI受精率、卵裂率和可用胚胎数比较,差异无统计学意义(P>0.05)。结论:严重少弱精患者处理后只要有足够的精子可行IVF短时受精、Re-ICSI,Re-ICSI和ICSI有相似的结局。
Objective: To observe the curative effect of short-term in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) on severely weakened patients. Methods: Retrospective analysis of 50 cycles of assisted reproductive treatment of semen parameters for the treatment of severe weak weakness in patients with the results. Results: IVF fertilization in 17 cycles and fertilization rate of IVF were lower than those in ICSI (P <0.05). However, there was no significant difference in the number of embryos and excellent embryos between the two groups (P> 0.05). IVF fertilization failed in 33 cycles and Re-ICSI in 31 cycles. There was no significant difference in ICSI, Re-ICSI fertilization rate, cleavage rate and number of available embryos between homologous eggs (P> 0.05). CONCLUSIONS: Re-ICSI, Re-ICSI, and ICSI have similar outcomes as long as sufficient sperm are available for IVF short-term fertilization after treatment in severely weakened patients with weakness.