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目的探讨新疆地区哈萨克族不同年龄组冠心病患者尿酸水平。方法随机选取2012年1月至2013年1月在新疆伊犁州友谊医院收治的哈萨克冠心病患者201例为研究对象。依据年龄段分为:20-39岁组20例;40-49岁组27例:50-59组60例;60-69岁组53例;超过70岁组41例。研究各组间男女患者的血尿酸水平。并用Logistic回归分析影响冠心病的因素。结果冠心病男性患者的血尿酸水平高于女性,且差异有统计学意义。男性患者的血尿酸水平随年龄增长而升高,但差异无统计学意义,40岁以上的女性患者血尿酸随年龄增长而升高,差异有统计学意义。经多元Logistic回归分析,对年龄、高血压、糖尿病、HDL-C、LDL-C、BMI进行校正后,高尿酸血症仍为冠心病发病的独立危险因素(OR=1.112,P=0.042)。结论新疆地区哈萨克族冠心病男性患者的血尿酸水平高于女性,且高尿酸血症为冠心病发病的独立危险因素。
Objective To investigate the uric acid levels in patients with coronary heart disease in different age groups in Kazak of Xinjiang. Methods A total of 201 Kazakh patients with coronary heart disease admitted from January 2012 to January 2013 in Yili Friendship Hospital of Xinjiang Uygur Autonomous Region were enrolled in this study. According to the age group: 20-39 years old group 20 cases; 40-49 years old group 27 cases: 50-59 group 60 cases; 60-69 years old group 53 cases; over 70 years old group 41 cases. Study of male and female patients in each group of uric acid levels. Logistic regression analysis was used to analyze the factors influencing coronary heart disease. Results The level of serum uric acid in CHD patients was higher than that in women, and the difference was statistically significant. Serum uric acid levels in male patients increased with age, but the difference was not statistically significant. The serum uric acid increased with age in female patients over the age of 40, the difference was statistically significant. After adjusting for age, hypertension, diabetes, HDL-C, LDL-C and BMI, multivariate Logistic regression analysis showed that hyperuricemia was still an independent risk factor for CHD (OR = 1.112, P = 0.042). Conclusion The prevalence of serum uric acid in Kazakh patients with coronary heart disease in Xinjiang is higher than that in women. Hyperuricemia is an independent risk factor for coronary heart disease.