患儿,女,2.5岁,第3胎,足月产,出生体重2.6kg。生后窒息,经抢救2分钟后缓解。患儿发育迟缓,智力低下,不会坐、不会说话,手不能握物,不能自己吃东西,大小便不能自理。父母非近亲,患儿出生时年龄均为29岁。前两胎均于孕3～4月时自然流产,此次孕早期服中药保胎。患儿外祖母曾有3次早期自然 Children, female, 2.5 years old, third child, full-term birth, birth weight 2.6kg. After birth, suffocation, relief after 2 minutes of rescue. Children with stunting, mental retardation, will not sit, can not speak, the hand can not hold things, can not eat their own, urine can not take care of themselves. Non-relatives of parents, children were born at the age of 29 years. The first two pregnancies were spontaneous abortion in pregnancy 3 to 4 months, the traditional Chinese medicine miscarriage early pregnancy. There were three early childhood natural grandmothers