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对近20年收治的526例短暂性脑缺血发作(TIA)患者的临床资料进行了回顾性分析,结果显示:①TIA发作时间为偏态分布,其中95%的患者发作时间在2.65小时以内,99%在5.37小时以内;②在198例有CT或MRI资料的TIA病例中,发现62例有与症状一致的梗塞灶,其中58例发作时间持续3小时以上,并且梗塞灶的出现与发作时间的长短呈正相关;③在167例有随访资料的病例中,131例发生脑梗塞,其发生机率与TIA发作时间的长短呈正相关。因此认为,传统TIA概念中的发作时间应调整为3小时内为宜,此与现代病理学与影像学结论相符,同时也有利于临床脑梗塞的诊治(特别是溶栓治疗)的顺利开展。
The clinical data of 526 patients with transient ischemic attack (TIA) admitted in the past 20 years were retrospectively analyzed. The results showed that: ① The onset of TIA was skewed, with 95% of the patients having episodes of 2.65 hours , 99% within 5.37 hours; ② In 198 cases of TIA with CT or MRI data, 62 cases were found consistent with the symptoms of infarction, of which 58 cases last more than 3 hours, and the infarction There was a positive correlation with the length of the attack time. ③ Among the 167 cases with follow-up data, 131 cases had cerebral infarction, and the incidence rate was positively correlated with the duration of TIA. So that the traditional concept of TIA attack time should be adjusted within 3 hours is appropriate, which is consistent with the conclusions of modern pathology and imaging, but also conducive to clinical diagnosis and treatment of cerebral infarction (especially thrombolytic therapy) carried out smoothly.