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本研究应用胎盘免疫调节因子（ＰＩＦ）辅助治疗恶性肿瘤３１３例，并以同期诊断相同的恶性肿瘤３１３例作对照，以观察其疗效及对免疫功能的影响。结果表明：治疗组病人体重较对照组明显增加（Ｐ＜０．００１）；ＣＤ＋３；ＣＤ＋４细胞、ＮＫ细胞活性和淋转率明显升高（Ｐ值均＜０．００１），ＣＤ＋８细胞降低，但未达显著水平。ＣＤ＋４／ＣＤ＋８细胞比值治疗后比治疗前也有明显提高（Ｐ＜０．０５），而对照组无差异；ＩｇＧ、ＩｇＭ水平有明显提高（Ｐ＜０．００１），ＩｇＡ水平有提高，但无显著差异。提示ＰＩＦ是一种较好的免疫调节剂和免疫增强剂，具有明显提高机体免疫功能作用
In this study, placental immunoregulatory factor (PIF) was used to treat 313 cases of malignant tumors, and 313 cases of the same malignant tumors were diagnosed in the same period as controls to observe its effect and influence on immune function. The results showed that the weight of the patients in the treatment group was significantly higher than that in the control group (P<0.001); the CD+3, CD+4 cells, NK cell activity and the rate of lymphocyte turnover were significantly higher (P<0.001), and the CD+8 cells were decreased. Not reaching a significant level. The ratio of CD+4/CD+8 cells was also significantly higher after treatment than before treatment (P<0.05), while there was no difference in the control group; the levels of IgG and IgM were significantly increased (P<0.001), and the level of IgA was increased, but there was no significant difference. difference. It is suggested that PIF is a better immunomodulator and immunopotentiator, which has a significant effect on improving the body’s immune function.