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目的：比较四逆扬（SD）和硝酸异山梨酯（ID）对冠心病心绞痛病人的疗效。方法：采用单盲、相互对照的设计方法，将30例冠心病病人随机分为SD组（15例）和ID组（15例），观察其心绞痛发作的程度、心电图的变化和血清中丙二醛（MDA）和超氧化物歧化酶（SOD）水平的变化。结果：SD和ID均能有效的缓解心绞痛的发作、改善心电图的缺血性ST－T改变，同时SD还有降低血清MDA、提高SOD以及改善心功能的作用。结论：SD具有与ID相似的临床效果，在降低MDA、升高SCD方面优于ID。
OBJECTIVE: To compare the efficacy of cis-reversol (SD) and isosorbide dinitrate (ID) in patients with coronary heart disease and angina pectoris. METHODS: Using a single-blind, cross-reference design method, 30 patients with coronary heart disease were randomly divided into SD group (15 cases) and ID group (15 cases) to observe the degree of angina attack, electrocardiographic changes, and serum gamma. Changes in aldehyde (MDA) and superoxide dismutase (SOD) levels. Results: Both SD and ID can effectively relieve the onset of angina pectoris, improve the electrocardiographic ischemic ST-T changes, and SD can also reduce serum MDA, increase SOD, and improve cardiac function. Conclusion: SD has clinical effects similar to ID, and is superior to ID in reducing MDA and increasing SCD.