鼻腔上颌窦恶性纤维组织细胞瘤是一种比较少见的恶性肿瘤,其临床表现酷似该部位的其他恶性肿瘤,但本病骨质破坏严重,范围广泛,对放疗和化疗不敏感,复发和转移率高,预后差,确诊主要依靠病理学检查,治疗关键在于早期诊断,早期治疗,彻底手术.本文报告5例,并结合文献,对其发病年龄,症状与体征,影像学特点,组织病理学特点,治疗及预后等进行了讨论. Nasal maxillary sinus malignant fibrous histiocytoma is a relatively rare malignancy, its clinical manifestations resemble other malignancies in this area, but the disease has serious bone destruction, a wide range of insensitivity to radiotherapy and chemotherapy, recurrence and metastasis rate High, poor prognosis, the diagnosis mainly depends on pathological examination, the key is the treatment of early diagnosis, early treatment, thorough surgery.This article reports 5 cases, combined with the literature, the incidence of age, symptoms and signs, imaging features, histopathological features , Treatment and prognosis were discussed.