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目的：了解慢性前列腺炎的致病菌及其对药物的敏感性。方法：对性病门诊215树前列腺液标本用常规血琼脂平板分离和纯化致病菌，采用美国Sceptor细菌鉴定仪及配套生化鉴定板和药敏试验板进行生化试验和药物敏感性试验。结果：分离出病原菌135株，分离阳性率为62．8％。以表皮葡萄球菌（45株）、金黄色葡萄球菌（39株）、大肠杆菌（16株）为最多见。药物敏感性试验结果显示，表皮葡萄球菌对万古霉素、克林霉素和利福平较敏感，金黄色葡萄球菌对头孢唑林、阿米卡星、万古霉素敏感性较高，而大肠杆菌对氨基糖苷类、头孢菌素类较敏感。同时检测出耐甲氧西林表皮葡萄球菌（MRSE）和耐甲氧西林金黄色葡萄球菌（MRSA）共14株。结论：性病门诊慢性前列腺炎的致病菌以葡萄球菌和大肠杆菌为最常见，其中MRSE和MRSA占分离病原菌的10．4％；细菌培养与药物敏感性试验对诊治慢性前列腺炎有较高的临床参考价值。
Objective: To understand the pathogens of chronic prostatitis and its sensitivity to drugs. Methods: The staphylococcal prostatic fluid samples of STD clinics were isolated and purified by routine blood agar plates. The biochemical test and drug susceptibility test were carried out by the American Sceptor bacteria identification kit, biochemical identification plate and drug sensitivity test plate. Results: 135 strains of pathogens were isolated and the positive rate was 62.8%. Staphylococcus epidermidis (45 strains), Staphylococcus aureus (39 strains), Escherichia coli (16 strains) for the most common. Drug sensitivity test results show that Staphylococcus epidermidis is more sensitive to vancomycin, clindamycin and rifampicin, Staphylococcus aureus higher sensitivity to cefazolin, amikacin, vancomycin, while the large intestine Bacillus aminoglycosides, cephalosporins are more sensitive. At the same time, 14 strains of methicillin-resistant Staphylococcus epidermidis (MRSE) and methicillin-resistant Staphylococcus aureus (MRSA) were detected. Conclusion: Staphylococcus aureus and Escherichia coli are the most common pathogens in STD clinics, of which MRSE and MRSA account for 10.4% of the total isolates of pathogens. Bacterial culture and drug susceptibility test are more effective in diagnosis and treatment of chronic prostatitis Clinical reference value.