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目的 :分析胰腺癌患者的临床特征。方法 :所有数据采用SPSS17.0统计软件分析。单因素分析采用Kaplan-Meier法;多因素分析采用Cox比例风险回归模型;以P<0.05为显著性差异。结果 :1.男女比例1.6:1,高发年龄段在60至70岁,首发症状以上腹痛为主。43.6%确诊时合并肝转移,肿瘤部位多位于胰头,占47.4%,39例有病理结果,其中,导管腺癌占94.9%。肿瘤分期以Ⅳ期为多,占58.3%。2.单因素分析结果 :年龄、上腹痛、肝转移、发现时肿瘤分期、治疗方式与预后密切相关(P<0.05)。多因素分析法结果显示:年龄、肿瘤分期为影响胰腺癌预后的独立因素(P<0.05)。结论 :1.年龄、肿瘤分期为影响胰腺癌预后的独立因素,并且呈正相关。2.胰腺癌早期行根治性手术治疗仍是胰腺癌的首选治疗方式。
Objective: To analyze the clinical features of patients with pancreatic cancer. Methods: All data were analyzed by SPSS17.0 statistical software. Kaplan-Meier method was used in univariate analysis; Cox proportional hazards regression model was used in multivariate analysis; P <0.05 was considered as significant difference. Results: 1 male to female ratio of 1.6: 1, high incidence of age in the 60 to 70 years old, the first symptom of abdominal pain above. 43.6% were diagnosed with liver metastasis, the tumor located in the head of the pancreas, accounting for 47.4%, 39 cases of pathological findings, of which, ductal adenocarcinoma accounted for 94.9%. Stage of tumor to more than Ⅳ, accounting for 58.3%. The results of univariate analysis: age, upper abdominal pain, liver metastasis, tumor staging found, the treatment and prognosis are closely related (P <0.05). Multivariate analysis showed that age and tumor stage were independent factors affecting the prognosis of pancreatic cancer (P <0.05). Conclusion: 1. Age and tumor stage are the independent factors affecting the prognosis of pancreatic cancer, and are positively correlated. 2. Radical pancreatic cancer surgery is still the preferred treatment of pancreatic cancer.