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作者为阐明食管癌术后放疗的效果,将1985~1989年期间82例食管癌术后预防性放疗病人与同期982例单纯手术病人进行对比观察。手术采用食管次全切除加食管周围脂肪组织和淋巴结、以及贲门、胃左淋巴结切除。放疗在术后2~6周开始,剂量为纵隔区50~60Gy/5~6周,双锁骨上区50Gy/5周。结果表明,Ⅱa期术后放疗病人5年生存率为42.0%,单纯手术组为26.0%(P<0.01)。Ⅲ期病人的5年生存率两组无差异(P>0.05),但术后放疗组逐年生存率略高于单纯手术组。结果提示,除0期病人外,食管癌术后均应进行放疗。
In order to elucidate the effect of postoperative radiotherapy for esophageal cancer, the authors compared 82 cases of postoperative radiotherapy for postoperative esophageal cancer between 1985 and 1989 with 982 patients undergoing surgery alone. Surgery used subtotal esophagectomy plus adipose tissue around the esophagus and lymph nodes, as well as cardia and left gastric lymph node dissection. Radiotherapy began at 2 to 6 weeks after surgery. The dose ranged from 50 to 60 Gy/5 to 6 weeks in the mediastinal area and 50 Gy/5 weeks in the double supraclavicular area. The results showed that the 5-year survival rate of patients with stage IIa postoperative radiotherapy was 42.0%, and that of the surgery alone group was 26.0% (P<0.01). The 5-year survival rate of stage III patients was not different between the two groups (P>0.05), but the yearly survival rate of postoperative radiotherapy group was slightly higher than that of the simple surgery group. The results suggest that radiotherapy should be performed after esophageal cancer except for patients with stage 0.