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中医认为,脾虚生化乏源可致气血亏虚,出现面色少华、形体消瘦、倦怠乏力等虚损证候,患者的抗病能力也受到影响。作者等在前一阶段工作中已发现,此种患者T细胞介导的细胞免疫功能低下,而后者又与同时存在的营养不良和贫血有一定关系”。在此基础上,作者通过限制小白鼠饮食中蛋白质和热量的摄入,造成蛋白质一能量营养不良和贫血,模拟人体“生化乏源”所致的气血亏虚状态,然后观察胸腺和脾脏这两个免疫器官的病理形态学政变,以验证临床研究的结论。
Chinese medicine believes that lack of source of spleen deficiency can lead to deficiency of qi and blood, appear deficiency syndrome, body weight loss, fatigue and fatigue, and the patient’s resistance to disease is also affected. In the previous phase of the work, the authors and others have found that T cell-mediated cellular immunity in this patient is low, and that the latter has a certain relationship with malnutrition and anemia that exist at the same time.” On this basis, the authors have restricted mice. The intake of protein and calories in the diet causes protein-energy malnutrition and anemia, mimicking the deficiency of blood and blood caused by the “biochemical deficiencies”, and then observing the pathological morphological coups of the two immune organs, the thymus and the spleen. To verify the conclusion of the clinical study.