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目的 探讨急性一氧化碳中毒后迟发性脑病 (DEACMP)的临床与磁共振成像 (MRI)特点。方法 分析 12例DEACMP患者的临床和MRI资料。结果 DEACMP患者的主要临床表现为以急性痴呆为特征的神经精神症状及体征。首发症状以痴呆 (83.3% )和尿失禁 (75 % )最多见。头部MRI的特征性表现为脑室周围白质和半卵圆中心双侧对称的点状、斑片状或融合性病灶 ,T2 加权呈高信号 ,T1加权呈低信号。病灶也可累及基底节区。 1例病灶主要位于大脑皮层。结论 本病的诊断主要依靠病史、临床表现和影像学检查。头部MRI对本病的诊断、鉴别诊断、观察疗效、判断预后具有重要的价值
Objective To investigate the clinical features and magnetic resonance imaging (MRI) of delayed encephalopathy after acute carbon monoxide poisoning (DEACMP). Methods Clinical and MRI data of 12 patients with DEACMP were analyzed. Results The main clinical manifestations of DEACMP were neuropsychiatric symptoms and signs characterized by acute dementia. The first symptom was dementia (83.3%) and urinary incontinence (75%) the most common. Head MRI features of bilateral periventricular white matter and semi-oval center symmetrical punctate, patchy or fusion lesions, T2 weighted high signal, T1 weighted low signal. Lesions may also involve the basal ganglia. One case was mainly located in the cerebral cortex. Conclusion The diagnosis of this disease depends mainly on medical history, clinical manifestations and imaging studies. Head MRI of the diagnosis of the disease, differential diagnosis, observation of efficacy, to determine the prognosis of great value