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背景:终末期肾脏疾病(ESRD)患者常有不能单纯以冠状动脉疾病(CAD)解释的心绞痛。其症状常由收缩和舒张功能障碍、心律失常和微血管病变引起。本研究提出肾衰竭患者心绞痛的另一种可能原因,即动力性左室梗阻(LVO)。方法:对125例拟实施肾脏移植的患者行多巴酚丁胺负荷超声心动图(DSE)及冠状动脉造影。LVO定义为LV流出道压力阶差峰值>50mmHg。
Background: End-stage renal disease (ESRD) patients often have angina pectoris that can not be interpreted solely on the basis of coronary artery disease (CAD). Symptoms often by the contraction and diastolic dysfunction, arrhythmia and microvascular disease caused. This study presents another possible cause of angina in patients with renal failure, dynamic left ventricular obstruction (LVO). Methods: Dobutamine stress echocardiography (DSE) and coronary angiography were performed in 125 patients undergoing kidney transplantation. LVO is defined as the LV outflow tract pressure gradient peak> 50mmHg.