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目的比较胰岛素泵连续皮下输注治疗与多次皮下注射胰岛素控制血糖的作用 ,以及在降低每日血糖波动、减少低血糖反应及改善生活质量的效果。方法 2 0例胰岛素治疗的高血糖患者 ,分别进行两种胰岛素强化治疗 :1胰岛素泵连续皮下输注治疗 ( CSII)组 8例 ;2多次皮下注射胰岛素 ( MSII)组 12例。结果两组治疗后血糖、糖化血红蛋白、平均胰岛素用量、低血糖发生率及达到靶血糖值时间均有显著差异。结论 CSII能更快、更有效地控制高血糖 ,在减少血糖波动、降低低血糖发生率及改善生活质量方面均有显著差异。
Objective To compare the effects of continuous subcutaneous infusion of insulin pump and subcutaneous insulin administration on blood sugar control, as well as the effect of reducing daily blood sugar fluctuation, reducing hypoglycemic reaction and improving quality of life. Methods Twenty patients with hyperglycemia treated with insulin were treated with two kinds of intensive insulin therapy: 1 in the CSII group and 8 in the subcutaneous injection of insulin (MSII) group. Results After treatment, the blood glucose, glycosylated hemoglobin, the average amount of insulin, the incidence of hypoglycemia and time to reach the target blood glucose values were significantly different. Conclusion CSII can control hyperglycemia faster and more effectively, with significant differences in reducing blood sugar fluctuation, lowering the incidence of hypoglycemia and improving the quality of life.