药物局部涂布法治疗口腔粘膜病变,往往因唾液及口腔组织的自洁作用,使药物难以有效地作用于局部。作者报道用博莱霉素离子导入法治疗癌前病变的白斑,获得良好的效果,并进行若干基础的实验研究。导入方法:将博莱霉素溶解于生理盐水。阳极为导入电极,阴极为无关电极,使导入电极通过含博莱霉素液的棉球与患部接 The topical application of drugs to the treatment of oral mucosal lesions, often due to the self-cleaning effect of saliva and oral tissues, makes it difficult for drugs to effectively act on the topic. The authors reported that the treatment of precancerous leukoplakia with bleomycin ion introduction method achieves good results and several basic experimental studies. Introduction method: Bleomycin is dissolved in physiological saline. The anode is the lead-in electrode and the cathode is the indifferent electrode. The lead-in electrode is connected to the affected part through the cotton ball containing the bleomycin liquid.