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目的:提高对小儿肺炎支原体(MP)肺炎的临床认识和诊治水平。方法:对2010年8月-2012年3月间108例确诊为MP肺炎住院患儿的临床特点进行总结和分析。结果:发病年龄多为学龄儿童,6~13岁占71.3%;持续发热伴刺激性咳嗽的患儿占77.7%,早期无明显阳性体征。用颗粒凝集法检测血清MP-IgM阳性率高(88.8%)。外周血白细胞正常占48%,但CRP大多升高(52.8%)。胸片以一侧大片絮状阴影为多见,占79.6%。28例有肺外合并症,占25.9%,常见渗出性胸膜炎,贫血、肝损害等。所有病例用阿奇霉素治疗效果良好,尚未发现耐药情况。结论:小儿MP肺炎好发于学龄儿童,颗粒凝集法检测血清MP-IgM阳性率高,有利于早期诊断。
Objective: To improve the clinical knowledge and diagnosis and treatment of children with Mycoplasma pneumoniae (MP) pneumonia. Methods: The clinical features of 108 hospitalized infants diagnosed as MP pneumonia from August 2010 to March 2012 were summarized and analyzed. Results: The age of onset was mostly school-age children, accounting for 71.3% of all patients aged 6-13 years. The incidence of persistent fever with irritating cough was 77.7%, with no obvious positive signs in early stage. Serum MP-IgM was detected by particle agglutination (88.8%). Normal peripheral blood leucocytes accounted for 48%, but CRP mostly increased (52.8%). Chest to one side of large floc shadows more common, accounting for 79.6%. 28 cases had extrapulmonary complication, accounting for 25.9%, common exudative pleurisy, anemia, liver damage and so on. All cases treated with azithromycin good effect, no drug resistance has been found. Conclusion: MP pneumonia in children occurs in school-age children. The positive rate of serum MP-IgM detected by particle agglutination is high, which is good for early diagnosis.