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将80例早期糖尿病肾病患者分为治疗组和对照组,两组在常规治疗基础上,治疗组静脉推注前列地尔(商品名:凯时)10μg,每日一次,连续14天。对照组不给上述治疗。控制血压、血脂、血糖等其他治疗方法两组相同。结果:两组总有效率比较有显著差异,治疗组优于对照组。结论:短期静脉应用前列地尔,对早期糖尿病肾病患者临床疗效满意,用药后6个月随访尿蛋白无明显回升。
Eighty patients with early diabetic nephropathy were divided into treatment group and control group. On the basis of routine treatment, the two groups were treated with intravenous alprostadil 10 g once daily for 14 days. The control group did not give the above treatment. Control of blood pressure, blood lipids, blood sugar and other treatments are the same in both groups. Results: The total effective rate was significantly different between the two groups, the treatment group was better than the control group. Conclusions: Short-term intravenous administration of alprostadil is satisfactory for the early stage of diabetic nephropathy, and there is no obvious recovery of urinary protein after 6 months of treatment.