目的探讨孤立性纤维性肿瘤的诊断及外科治疗方法。方法回顾我院10年来经手术切除并行病理检查确诊为孤立性纤维性肿瘤的病例资料,就其诊断和外科治疗方法进行总结与分析。结果共16例次患者,肿瘤分别位于胸腔、腹股沟、后腹膜、外阴、颈部、下肢等部位,无明显特异的临床症状。所有病例均行手术完全切除肿瘤,术后经病理学检查和免疫组化染色检查确诊。对患者定期随访,其中2例分别于术后5年和7年肿瘤复发,2例分别随访3年和5年后失访,2例患者分别于随访的第9个月和16个月因全身多发转移死亡,其余患者仍在随访中。结论孤立性纤维性肿瘤大多数病例表现为局部缓慢生长的无痛性肿块,无明显的临床症状,术前诊断较困难,目前仅能依靠术后免疫组化检查确诊,手术切除是最佳的治疗方法。 Objective To investigate the diagnosis and surgical treatment of solitary fibrous tumor. Methods The data of cases with isolated fibrous tumors confirmed by surgical resection and pathological examination in our hospital over the past 10 years were reviewed and their diagnosis and surgical treatment methods were summarized and analyzed. Results A total of 16 cases of patients with tumors were located in the chest, groin, retroperitoneal, vulvar, neck, lower extremities and other parts, no specific clinical symptoms. All cases underwent surgical resection of the tumor completely, postoperative pathological examination and immunohistochemical examination confirmed. Two patients were followed up for 5 years and 7 years respectively. Two patients were followed up for 3 years and 5 years respectively. Two patients were followed up for 9 months and 16 months respectively. Multiple metastasis deaths, the remaining patients are still under follow-up. Conclusions Most of the solitary fibrous tumors are painless masses with slow growth. There are no obvious clinical symptoms. Preoperative diagnosis is more difficult. At present, only immunohistochemical examination is the best method to diagnose solitary fibrous tumors. Surgical resection is the best treatment method.