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自体激泌素的分泌是恶性转化在分子水平以及细胞基础上提出的一种假说。在癌基因与肽类生长因子不同领域的研究中发现恶性肿瘤细胞的癌基因与自主性生长因子有关。恶性细胞内源性产生肽类生长因子作用于自己的受体,其表现型的表达过程称“自体激泌素的分泌”。自体激泌素假说的证据:在肿瘤细胞中,自体激泌素包括的生长因子有α型转化生长因子(TGFα)、与血小板生长因
The secretion of autokinin is a hypothesis that malignant transformation is proposed at the molecular level as well as on the cellular basis. In the different fields of oncogenes and peptide growth factors, the oncogenes of malignant tumor cells were found to be related to autonomous growth factors. The malignant cells endogenously produce peptide growth factors that act on their own receptors, and their phenotypic expression process is called “secretase secretion.” Evidence of autohypotensin hypothesis: In tumor cells, autologous growth factors include growth factor alpha transforming growth factor (TGF alpha), and platelet growth factors.