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目的分析血液透析联合血液灌流治疗尿毒症并发症的疗效。方法 56例尿毒症患者,根据治疗方法不同分为观察组和对照组,各28例。观察组采用血液透析联合血液灌流,对照组采用血液透析。比较两组临床疗效。结果两组患者治疗后β2微球蛋白、甲状旁腺激素及血红蛋白比较差异有统计学意义(P<0.05);两组治疗后肌酐、尿素氮比较差异无统计学意义(P>0.05)。治疗后,观察组难治性高血压、皮肤瘙痒、食欲不振缓解率分别为81.25%、89.47%、80.00%,均高于对照组的46.67%、50.00%、50.00%(P<0.05)。结论采用血液透析联合血液灌流方法治疗尿毒症并发症,治疗效果良好,有效清除其中毒性分子。
Objective To analyze the therapeutic effect of hemodialysis combined with hemoperfusion on the complications of uremia. Methods Fifty-six patients with uremia were divided into observation group and control group according to different treatment methods, 28 cases in each group. The observation group was hemodialysis combined with hemoperfusion, while the control group was hemodialysis. The clinical efficacy of the two groups were compared. Results The difference of β2 microglobulin, parathyroid hormone and hemoglobin in the two groups after treatment was statistically significant (P <0.05). There was no significant difference in creatinine and urea nitrogen between the two groups after treatment (P> 0.05). After treatment, the refractory hypertension, pruritus and loss of appetite in the observation group were 81.25%, 89.47% and 80.00%, respectively, which were all higher than those in the control group (46.67%, 50.00%, 50.00%, P <0.05). Conclusion hemodialysis combined with hemoperfusion method for the treatment of uremia complications, the treatment effect is good, effective removal of toxic molecules.