该校生化教研室博士颜面真的协成芝教授指是下,成功地表达了假肥大型肌营养不良症(DMD)cDNA基因片段并制备出其特异性抗血清,大大推进了对DMD的诊治工作,属国内首创。 DMD常见于男性,为X连锁隐性致死性遗传病,可靠诊断,携带者检出与产前诊断是预防本病的唯一有效措施。cDNA5-7kb片段位于DMD基因缺失突变热点区,选择性表达该区段基因,制备特 The biochemistry teaching and research faculty of the school is really Professor Cheng Zhi Zhi is the next, the successful expression of Duchenne muscular dystrophy (DMD) cDNA gene fragments and preparation of its specific antiserum, which greatly promoted the diagnosis and treatment of DMD , Is a domestic initiative. DMD is common in men, X-linked recessive lethal genetic disease, reliable diagnosis, carrier detection and prenatal diagnosis is the only effective way to prevent the disease. The cDNA5-7kb fragment is located in the hot spot of the deletion mutation of DMD gene and selectively expresses the segmental gene,