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目的 :探讨提高常年性变应性鼻炎 (PAR)疗效的治疗方法。方法 :将 10 5例 PAR患者随机分为 A、 B两组 ,A组 5 8例 ,联合使用鼻腔局部应用类固醇二丙酸倍氯松、抗组胺药盐酸西替利嗪和鼻内窥镜下筛前神经射频治疗 ,B组 4 7例 ,联合使用二丙酸倍氯松、盐酸西替利嗪综合治疗。结果 :随访 1年 ,A组总有效率达 94 .83% (其中显效 4 2例 ) ,B组为 95 .74 %(其中显效 30例 ) ;A组复发率 5 1.72 % ,B组为 72 .34% ,但复发病例 90 .6 3% (5 8/ 6 4 )的复发症状较治疗前为轻。两组总有效率经χ2 检验差异无显著性 (P >0 .0 5 ) ,复发率差异有显著性 (P <0 .0 5 )。 A、 B两组均无严重并发症发生。结论 :综合疗法治疗 PAR具有设计合理 ,疗效显著 ,疗程短等优点 ,有较好临床应用价值
Objective: To explore the treatment of perennial allergic rhinitis (PAR). Methods: A total of 105 patients with PAR were randomly divided into A and B groups. A group (58 cases) was treated with topical nasal application of beclomethasone dipropionate, antihistamine cetirizine hydrochloride and nasal endoscopy Under the screen before the nerve radiofrequency treatment, B group 47 cases, the combination of dipropionate dipicolinate, cetirizine hydrochloride comprehensive treatment. Results: The follow-up of 1 year showed that the total effective rate in group A was 94.83% (42 cases were markedly effective), 95.74% in group B (30 cases were markedly effective), the recurrence rate was 5.72% in group A and 72 .34%, but 90.63% (58/64) of recurrent cases were more likely to relapse than those before treatment. There was no significant difference in the total effective rate between the two groups (χ2 test, P> 0.05). The recurrence rate was significantly different (P <0.05). A, B, no serious complications occurred in both groups. Conclusion: The combination therapy of PAR has the advantages of reasonable design, significant curative effect, short course of treatment and so on, and has good clinical value