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目的:旨在研究脑心通胶囊联合西医治疗缺血性脑卒中颈动脉粥样硬化患者的临床研究。方法:选自抚顺市中心医院2014年1月-2015年1月神经内科门诊就诊或住院的患者共80例。随机分为治疗组和对照组各40例。对照组只给予西医常规治疗(阿托伐他汀),治疗组在西医常规治疗的基础上给予脑心通胶囊,疗程6个月。分别于治疗前,治疗后1个月、3个月、6个月观察患者的颈动脉斑块、颈动脉内膜中层厚度、血脂、纤维蛋白质(FIB)、超敏C反应蛋白(hs-CPR)的变化。结果:两组治疗后,颈动脉斑块和颈动脉内膜中层厚度均有明显降低,且治疗组改变明显优于对照组(P<0.05),差异有统计学意义;血脂水平、FIB水平及hs-CPR水平均有所降低,且治疗组较对照组均有明显降低(P<0.05),差异有统计学意义。结论:脑心通胶囊联合西药治疗缺血性脑卒中伴颈动脉粥样硬化患者疗效显着。
Objective: To study the clinical study of Naoxintong capsule combined with western medicine in the treatment of ischemic stroke patients with carotid atherosclerosis. Methods: A total of 80 patients were selected from neurological outpatients or hospitalized in Fushun Central Hospital from January 2014 to January 2015. Randomly divided into treatment group and control group of 40 cases. The control group was given routine western medicine treatment (atorvastatin). The treatment group was given Naoxintong capsule on the basis of routine treatment of Western medicine for 6 months. Carotid artery plaque, carotid artery intima-media thickness, serum lipids, fibrin (FIB), high sensitivity C-reactive protein (hs-CPR )The change. Results: After treatment, carotid artery plaque and carotid artery intima-media thickness were significantly decreased, and the treatment group changed significantly better than the control group (P <0.05), the difference was statistically significant; blood lipid levels, FIB levels and hs-CPR levels were reduced, and the treatment group were significantly lower than the control group (P <0.05), the difference was statistically significant. Conclusion: Naoxintong capsule combined with Western medicine in the treatment of ischemic stroke with carotid atherosclerosis patients with significant effect.