紫杉醇是治疗卵巢癌、乳腺癌等多种癌症的最重要的抗癌剂之一,主要资源是短叶红豆杉TaxusbrevifoliaNutt.的树皮。精制的紫杉醇仅约占树皮干质量的0.01%。由于其自然资源有限,近年来大多通过组织培养或细胞培养法来制备紫杉烷类。现有的通过溶剂萃取和色谱工艺的精制方法,主要 Paclitaxel is one of the most important anti-cancer agents for the treatment of various cancers such as ovarian cancer and breast cancer. The main resource is the bark of Taxus brevifolia Nutt. The refined paclitaxel accounts for only about 0.01% of the dry bark mass. Because of its limited natural resources, taxanes have been mostly prepared in recent years by tissue culture or cell culture methods. Existing purification methods through solvent extraction and chromatographic processes