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对15例慢性阻塞性肺疾病(COPD)并发肺心病患者进行核素心血池显像检查,并与右心导管测压作对照。结果显示:肺心病伴肺动脉高压组的右室射血分数(RVEF)较正常对照组和肺心病伴肺动脉压正常组均明显降低(P<0.001,P<0.001),右房舒张早期排空率(RAER)和右室峰充盈率(RVPFR)呈阶梯样降低,且RAER和RVPFR的下降出现在RVEF下降之前。提示右室舒张功能可能先于收缩功能受损。
Fifteen patients with chronic obstructive pulmonary disease (COPD) complicated with pulmonary heart disease were examined by radionuclide venography and compared with right cardiac catheterization. The results showed that right ventricular ejection fraction (RVEF) in patients with pulmonary heart disease and pulmonary hypertension was significantly lower than those in normal controls and patients with pulmonary heart disease and pulmonary hypertension (P <0.001, P <0.001) RAER and RVPFR decreased stepwise, and the decline of RAER and RVPFR occurred before the decline of RVEF. Tip right ventricular diastolic function may be impaired contractile function.