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对高血压急症患者应尽快给予快速降压治疗,硝苯吡啶和可乐定是近年来常用的药物.本文研究目的旨在比较此二药对高血压急症的临床疗效和其安全性。研究对象包括51例舒张压≥16.0kPa的高血压患者,男性20例,女性31例,平均年龄48.2岁,随机分为两组.①硝苯吡啶组23例:一次顿服硝苯吡啶20mg,服后2小时内96％的病例舒张压降至≤14.7kPa,而83%的病例在服药后45分钟内即可达到这一水平.服药后45分钟时平均舒张压下降3.83kPa,收缩压下降6.27kPa,但30%的病例于服药后3小时血压又逐渐恢复至服药前水平。服药
For patients with acute hypertension should be given as soon as possible rapid antihypertensive treatment, nifedipine and clonidine are commonly used drugs in recent years.This study aims to compare the two drugs on the clinical efficacy and safety of hypertensive emergency. The study included 51 hypertensive patients with diastolic blood pressure≥16.0kPa, 20 males and 31 females, with an average age of 48.2 years.All the patients were randomly divided into two groups: ① nifedipine group (n = 23) Ninety-two percent of patients experienced a decrease in diastolic blood pressure to <14.7 kPa within 2 hours of administration, whereas 83% of patients achieved this level within 45 minutes of taking the medication.43 The mean diastolic blood pressure decreased by 3.83 kPa at 45 minutes and the systolic blood pressure decreased 6.27kPa, but 30% of the cases in the medication 3 hours after the blood pressure and gradually returned to pre-dose levels. Take medicine