论文部分内容阅读
AFP是由胎儿肝细胞、卵黄囊细胞合成的正常血清蛋白,在胎儿胃肠道中亦有微量合成。在成人血清AFP的检出,最初曾诊断为肝细胞癌和含有卵黄囊细胞成分的畸胎瘤。但是,血清AFP的轻度升高亦偶见于伴有大量肝转移的胃肠道恶性肿瘤。近来发现,血清AFP的升高可见于某些非恶性肝病患者,尤其是在急性和慢性病毒性肝炎恢复期。某些学者推测由于肝脏再生引起了AFP的合成和释放。
AFP is a normal serum protein synthesized by fetal liver cells and yolk sac cells and is also synthesized in the fetal gastrointestinal tract. Detection of adult serum AFP was initially diagnosed as hepatocellular carcinoma and teratoma containing yolk sac cell components. However, a slight increase in serum AFP is also occasionally seen in gastrointestinal malignancies with a large number of liver metastases. Recently, it has been found that elevation of serum AFP can be seen in some patients with non-malignant liver diseases, especially in the recovery period of acute and chronic viral hepatitis. Some scholars speculate that the synthesis and release of AFP is due to liver regeneration.