论文部分内容阅读
目的评价吡格列酮联用二甲双胍治疗2型糖尿病的临床疗效。方法将240例2型糖尿病患者随机分为两组,治疗组采用吡格列酮联用二甲双胍治疗,对照组单用二甲双胍治疗,比较两组血糖和胰岛素等指标的变化。结果连用6个月后两组空腹血糖(FPG)、餐后2 h血糖(P2hBG)、糖化血红蛋白(HbAlc)、空腹胰岛素(FINS)、餐后2 h胰岛素(P2hlNS)水平均明显降低,与治疗前比较差异均有统计学意义(P<0.05)。结论吡格列酮联用二甲双胍治疗2型糖尿病,能够明显降低血糖水平,改善胰岛素状态。
Objective To evaluate the clinical efficacy of pioglitazone combined with metformin in the treatment of type 2 diabetes mellitus. Methods 240 patients with type 2 diabetes were randomly divided into two groups. The treatment group was treated with pioglitazone combined with metformin. The control group was treated with metformin alone. The changes of blood glucose and insulin were compared between the two groups. Results After 6 months, FPG, P2hBG, HbAlc, FINS and P2hlNS in both groups were significantly lower than those in the control group Before the difference was statistically significant (P <0.05). Conclusions Pioglitazone combined with metformin in the treatment of type 2 diabetes can significantly lower blood glucose levels and improve insulin status.