论文部分内容阅读
目的 :研制氟罗沙星葡萄糖注射液。方法 :通过提高氟罗沙星的溶解度和稳定性 ,确定处方和制备工艺。结果 :用乳酸调节pH值 ,确定注射液的最佳 pH值为 3 .5～ 4 .5。 结论 :经稳定性考察 ,氟罗沙星葡萄糖注射液的质量符合药典规定的注射剂标准
Objective: To develop fleroxacin glucose injection. Methods: By improving the solubility and stability of fleroxacin, prescription and preparation process were determined. Results: The pH of lactic acid was adjusted to determine the optimum pH of the injection was 3.5 ~ 4.5. Conclusion: The stability of flefloxacin glucose injection in accordance with the quality of the provisions of the Pharmacopoeia injection standards