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目的探讨他汀类药物在急性冠脉综合征治疗中的作用。方法选取2008年1月至2010年11月诊治的急性冠脉综合征患者707例,随机分为他汀组363例,对照组344例,观察两组病例病死率。结果他汀组死亡13例,病死率3.58%;对照组死亡29例,病死率8.43%,两组死亡率比较P<0.01差异有统计学意义。结论在针对急性冠脉综合征患者治疗中除了积极应用基础治疗,应加强他汀类药物应用,可以有效的稳定稳定冠脉粥样斑块,降低病死率。
Objective To investigate the role of statins in the treatment of acute coronary syndromes. Methods A total of 707 patients with acute coronary syndrome who were diagnosed and treated from January 2008 to November 2010 were randomly divided into statin group (363 cases) and control group (344 cases). The mortality of two groups was observed. Results Thirteen patients died in the statin group, with a mortality rate of 3.58%. In the control group, 29 patients died and the case fatality rate was 8.43%. There was significant difference in mortality between the two groups (P <0.01). Conclusion In the treatment of patients with acute coronary syndromes, in addition to the active application of basic treatment, should be strengthened statin application, can effectively stabilize and stabilize coronary atherosclerotic plaque, reduce mortality.