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乙型肝炎的发病与机体的细胞免疫功能有密切关系。国内外许多资料表明,慢性乙型肝炎细胞免疫功能低下,因此,曾设想用增强机体免疫功能的方法来促进肝炎的恢复。免疫核糖核酸(iRNA)是一种免疫增强剂,它是由HBsAg 免疫动物从其致敏的淋巴样组织中,用热酚或冷酚法提取出来的一种具有过继免疫活性的物质。目前,国内已用HBsAgiRNA 进行了一些基础和临床的工作。
The incidence of hepatitis B and the body’s cellular immune function are closely related. Many domestic and foreign data show that chronic Hepatitis B cell immune dysfunction, therefore, had envisaged to enhance the body’s immune function to promote the recovery of hepatitis. Immuno-ribonucleic acid (iRNA) is an immunopotentiating agent that is used to immunize an animal from its sensitized lymphoid tissue by HBsAg, using a hot phenol or a cold phenolic method to extract a substance with an inherited immunological activity. At present, some basic and clinical work has been done in China with HBsAgiRNA.