论文部分内容阅读
代谢综合征是多种代谢异常同时发生于同一个体的临床现象,胰岛素抵抗是代谢综合征的中心环节。膳食中脂肪的摄入总量和种类的不同都与胰岛素敏感性密切相关。当脂肪供能占总热量35%~40%以上时,会降低胰岛素敏感性。脂肪供能占总热量的35%~40%以下时,强调摄入脂肪酸的类型比脂肪摄入总量更为重要。人体研究表明饱和脂肪酸(SFA)增加胰岛素抵抗,而单不饱和脂肪酸(MUFA)和n-6多不饱和脂肪酸(PUFA)可改善胰岛素敏感性,n-3 PUFA对人体胰岛素敏感性没有影响。代谢综合征中的其他代谢异常成分也均受到膳食脂肪的影响。
Metabolic syndrome is a clinical phenomenon in which many metabolic abnormalities occur simultaneously in the same individual. Insulin resistance is the central part of metabolic syndrome. The total amount and type of fat intake in the diet are closely related to insulin sensitivity. When fat energy accounts for more than 35% of total calories 40%, will reduce insulin sensitivity. When fat energy accounts for 35% to 40% of the total calories, it is more important to emphasize that the type of fatty acid intake is more than the total fat intake. Human studies have shown that saturated fatty acids (SFA) increase insulin resistance, while monounsaturated fatty acids (MUFA) and n-6 polyunsaturated fatty acids (PUFA) improve insulin sensitivity, n-3 PUFA has no effect on human insulin sensitivity. Other metabolic abnormalities in the metabolic syndrome are also affected by dietary fat.