自Daffos等首次描述经腹壁在宫内抽取脐血样本以来,应用脐穿刺术进行快速胎儿染色体核型分析这一技术已被多数作者采用。本文报告了Vanderbili大学医学中心对96例孕妇的105例胎儿进行脐穿刺术及快速染色体核型分析的经验。手术前进行遗传咨询及高分辨超声检查,以确定胎儿异常程度。根据Daffos等所述方法,在超声引导下,经脐带抽取胎血样 Since Daffos et al. First described cord blood sampling in the uterus via the abdominal wall, the technique of rapid fetal karyotyping using umbilical cord aspiration has been adopted by most authors. This article reports on the experience of umbilical aspiration and rapid karyotype analysis of 105 fetuses from 96 pregnant women at Vanderbili University Medical Center. Preoperative genetic counseling and high-resolution ultrasound to determine the degree of fetal abnormalities. Fetal blood samples were drawn via the umbilical cord under ultrasound guidance as described by Daffos et al