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糖尿病是一种以血葡萄糖升高为主要特征的代谢性疾病，视网膜病变为其常见的并发症之一。众多研究表明，糖尿病视网膜病变（ DR）患者的心脑血管疾病（如脑卒中、冠心病、心力衰竭）风险增加。眼底血管是全身唯一可以直接观察的微血管，视网膜微血管系统为评估糖尿病患者心脑血管并发症提供了独一无二的“窗口”。该文主要总结DR与心脑血管疾病的关系，并探讨糖尿病血管并发症的病理生理学机制及治疗方法。“,”Diabetes mellitus is a kind of metabolic disease mainly characterized by hyperglycemia .Reti-nopathy is one of the most common complications of diabetes .Extensive studies have showed that patients with diabetic retinopathy( DR) have a higher risk of cardio-cerebrovascular diseases,such as stroke,coronary heart disease and heart failure.Since retinal vessel system is the only microvasculature which can be directly observed in the whole body,the assessment of retinopathy signs presents clinicians an unique opportunity to assess the diabetic cardio-cerebrovascular complications.Here is to make a review of the relationship between DR and cardio-cerebrovascular diseases and make a discussion on the pathophysiological mechanisms of dia-betic vascular complications and the treatments for them .