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自1988年2月奥美拉唑首次在瑞典上市以来,质子泵抑制剂已引起人们的极大关注;发展迅速,并被认为是继H_2受体阻滞剂之后抗溃疡药物领域的最大进步。
Proton pump inhibitors have drawn great attention since the first omeprazole marketed in Sweden in February 1988; they have developed rapidly and are considered to be the most significant advance in anti-ulcer drugs following H-2 blockers.