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本文对由6B、14、19F和23F型肺炎球菌荚膜多糖(PS)和脑膜炎球菌外膜蛋白复合物(OMPC)组成的4价肺炎球菌PS-脑膜炎球菌OMPC结合菌苗(Pnc OMPC)在婴幼儿中的免疫原性进行了研究。作者把62名婴儿分为A、B两组,A组,27人,于2、4和6月龄接种Pnc OMPC,于7和14月龄时采血;B组,35人,于4、6和14月龄接种,于7和15月龄时采血,31名幼儿于24月龄时接种1剂菌苗,其中10人于26月龄时加强接种1剂,于27月龄时采血。
In this paper, a four-valent pneumococcal PS-meningococcal OMPC-binding vaccine (Pnc OMPC) consisting of pneumococcal capsular polysaccharides 6B, 14, 19F, and 23F, and meningococcal outer membrane protein complex (OMPC) Immunogenicity in infants and young children was studied. The authors divided 62 infants into groups A and B, group A, 27, and Pnc OMPCs at 2, 4 and 6 months of age, and blood samples at 7 and 14 months of age; group B, 35, Were vaccinated at 14 months, blood was collected at 7 and 15 months of age, and 31 children were vaccinated at 24 months of age with one vaccine, of whom 10 were boosted at 26 months of age and one at 27 months of age.