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目的观察牙周局部应用盐酸米诺环素软膏治疗慢性牙周炎的临床效果。方法选取我科2007年治的140例慢性牙周炎患者随机分为观察组(盐酸米诺环素软膏辅助治疗组)和对照组(常规治疗组),比较两组患者的治疗效果。结果观察组显效42例,有效28例,总有效率为97.2%;对照组显效27例,有效31例,总有效率为85.3%。两组患者比较差异有统计学意义﹙P<0.01﹚,具有统计学意义。结论局部应用盐酸米诺环素软膏治疗牙周炎,能够有效地改善临床症状,获得较好的临床效果。
Objective To observe the clinical effect of periodontal topical application of minocycline hydrochloride ointment in the treatment of chronic periodontitis. Methods A total of 140 patients with chronic periodontitis who were treated in our department in 2007 were randomly divided into observation group (minocycline hydrochloride ointment adjuvant therapy group) and control group (conventional therapy group). The therapeutic effect was compared between the two groups. Results The observation group was effective in 42 cases, effective in 28 cases, the total effective rate was 97.2%; the control group markedly effective in 27 cases, effective in 31 cases, the total effective rate was 85.3%. The difference between the two groups was statistically significant (P <0.01), with statistical significance. Conclusion Local application of minocycline hydrochloride ointment for periodontitis can effectively improve the clinical symptoms and obtain better clinical results.