本文报告100例经胃镜活检标本尿素酶试验诊断幽门弯曲菌感染,阳性率60％。慢性活动性浅表性胃炎,萎缩性胃炎,消化性溃疡其阳性率分别为82.3％,71.4％和56.5％。尿素酶试验与病理片上幽门弯曲菌检出总的符合率为90％。78.3％的阳性在30分钟内出现。该试验简速准确,特异性高。幽门弯曲菌感染可能是慢性活动胃炎的主要病因和消化性溃疡的主要促发因素。 This article reports 100 cases of gastroscopy biopsy urease test diagnosis of Campylobacter pylori infection, the positive rate of 60%. Chronic active superficial gastritis, atrophic gastritis, peptic ulcer the positive rates were 82.3%, 71.4% and 56.5%. The total coincidence rate of urease test and Campylobacter pylori in pathology was 90%. 78.3% of positives appear within 30 minutes. The test is simple, accurate and specific. Campylobacter pylori infection may be the main cause of chronic active gastritis and peptic ulcer main contributing factors.