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探讨ω３多不饱和脂肪酸及牛碘酸，对大鼠脑神经发育是否存在协同的促进作用。方法将断乳仔鼠随机分成４组，每组１０只，（１）正常对照组（ＮＧ），（２）ω３多不饱和脂肪酸组（ω３Ｇ），（３）牛磺酸组（ＴＧ），（４）牛磺酸＋ω３多不饱和脂肪酸组（Ｔω３）。其中（１）ＮＧ组喂饲普通饲料并灌胃生理盐水，（２）ω３Ｇ组喂饲普通饲料并灌胃ω３多不饱和脂肪酸（３）ＴＧ组喂饲添加０．６％牛磺酸饲料（在普通料基础上）并灌胃生理盐水（４）Ｔω３组亦喂饲添加０．６％牛磺酸饲料并灌胃ω３多不饱和和脂肪酸。以上各组灌胃剂量皆为０．２ｍｌ／１０ｇｗｔ，共持结１个月。以大鼠学习行为、脑干听觉诱发电位（ＢＡＥＰ）及突触定量分析３个方面作为检测脑神经发育的指标。结果（１）Ｔω３组大鼠主动回避反应习得率（ＡＡＲＲ）（６４％）明显高于ω３Ｇ组（４５％）及ＴＧ组（＄÷％）（Ｐ＜０．０１）；三者均高于ＮＧ组（２５％）（Ｐ＜０．０１）。其中ω３ＧＶＳＮＧＰ＜０．０５）。（２）Ｔω３组大鼠脑干听觉诱发电位（ＢＡＥＰ）Ⅰ～Ⅴ波峰间期（ＩＰＬ）与ω３Ｇ组及ＴＧ组相比无统计学意义（Ｐ＞０．０５），但呈缩短趋势。三者Ⅰ～Ⅴ波ＩＰＬ均短于ＮＧ组（Ｐ＜０．０１）。（３）?
To investigate whether ω3 polyunsaturated fatty acids and perididic acid have a synergistic effect on brain development in rats. Methods Weaning offspring rats were randomly divided into 4 groups (n = 10): (1) normal control group (NG), (2) ω3 polyunsaturated fatty acid group (4) taurine + ω3 polyunsaturated fatty acid group (Tω3). (1) The NG group was fed with normal diet and normal saline, (2) Omega 3G group was fed normal diet and orally administered omega-3 polyunsaturated fatty acids (3) TG group was fed with 0.6% taurine diet On the basis of ordinary materials) and gavage with saline (4) The Tω 3 group was also fed with 0.6% taurine feed and orally administered omega-3 polyunsaturated and fatty acids. Gavage dose of the above groups are all 0.2ml / 10gwt, a total of 1 month. Three aspects of learning behavior, brainstem auditory evoked potentials (BAEP) and synaptic quantitative analysis were used as indicators of brain development. Results (1) The AARR (64%) in the Tω 3 group was significantly higher than that in the ω3G group (45%) and the TG group ($ ÷%) (P <0.01) In the NG group (25%) (P <0.01). Where ω3GVSNGP <0.05). (2) Compared with ω3G group and TG group, there was no significant difference in Ⅰ ~ Ⅴ peak interval (IPL) between BAEP group and Tω3 group (P> 0.05), but the trend was shortened. The IPLs of Ⅰ ~ Ⅴ wave were shorter than that of NG group (P <0.01). (3)?