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目的 :探析脉搏波速度(PWV)、踝臂指数(ABI)、C反应蛋白(CRP)在早期诊断老年冠心病(CHD)患者中的临床意义。方法 :分析2013年2月~2015年6月在我院接受治疗并已诊断或接受冠脉造影术拟诊的188例CHD老年女性患者的临床资料,根据入选者是否发生冠脉病变分为非冠脉病变组(非冠脉组,43例)和冠脉病变组(冠脉组,145例)两组。另外选取我院同期接受健康体检的38例健康体检老年女性者作为本次研究的对照组。比较三组的一般资料、血脂水平以及ABI、PWV、CRP水平。结果 :冠脉组、非冠脉组舒张压(DBP)和收缩压(SBP)明显高于对照组,而年龄、BMI以及FBG差异不明显。冠脉组、非冠脉组的TG、TC、LDL-C水平较对照组明显增高;冠脉组HDL-C水平明显低于对照组。冠脉组、非冠脉组的ba PWV、hs-CRP水平明显高于对照组;与非冠脉组比较,冠脉组的ba PWV、hs-CRP水平明显增高。结论 :联合检测老年CHD女性患者的ABI、PWV、CRP水平,具有重要的临床诊断价值。
Objective: To investigate the clinical significance of pulse wave velocity (PWV), ankle brachial index (ABI) and C-reactive protein (CRP) in the early diagnosis of elderly patients with coronary heart disease (CHD). Methods: The clinical data of 188 elderly female patients with CHD treated in our hospital from February 2013 to June 2015 who had been diagnosed or undergone coronary angiography were analyzed. According to whether the patients had coronary artery lesions or not, Coronary lesions (non-coronary group, 43 cases) and coronary lesions (coronary group, 145 cases) two groups. In addition, we selected 38 healthy elderly women who received physical examination in the same period of our hospital as the control group. The general data of three groups, blood lipid levels, ABI, PWV and CRP levels were compared. Results: Diastolic blood pressure (DBP) and systolic blood pressure (SBP) in coronary artery and non-coronary artery group were significantly higher than those in control group, but there was no significant difference in age, BMI and FBG. The levels of TG, TC and LDL-C in coronary artery and non-coronary artery group were significantly higher than those in control group. HDL-C level in coronary artery group was significantly lower than that in control group. The levels of ba PWV and hs-CRP in coronary artery group and non-coronary artery group were significantly higher than those in control group. Compared with non-coronary group, ba PWV and hs-CRP levels in coronary artery group were significantly increased. Conclusion: The combined detection of ABI, PWV and CRP levels in elderly CHD women has important clinical diagnostic value.